Saliva is a powerful painkiller

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Saliva is a powerful painkiller

I think nature knew this all along, dogs lick their wounds, people made poultices from chewing bread and sticking it on cuts. Natural healing is being found out by science.

Saliva from humans has yielded a natural painkiller up to six times more powerful than morphine, researchers say.

The substance, dubbed opiorphin, may spawn a new generation of natural painkillers that relieve pain as well as morphine but without the addictive and psychological side effects of the traditional drug.

When the researchers injected a pain-inducing chemical into rats’ paws, 1 gram of opiorphin per kilogram of body weight achieved the same painkilling effect as 3 grams of morphine.

The substance was so successful at blocking pain that, in a test involving a platform of upended pins, the rats needed six times as much morphine as opiorphin to render them oblivious to the pain of standing on the needle points.
Anti-depressive angle

“Its pain-suppressive effect is like that of morphine,” says Catherine Rougeot at the Pasteur Institute in Paris, France, who led the research. “But we have to test its side effects as it is not a pure painkiller,” she says. “It may also be an anti-depressive molecule.”

Rougeot and colleagues discovered that opiorphin works in nerve cells of the spine by stopping the usual destruction of natural pain-killing opiates there, called enkephalins.

Opiorphin is such a simple molecule that it should be possible to synthesise it and produce large quantities without having to isolate it from saliva, Rougeot explains. Alternatively, it might be possible to find drugs which trigger patients’ bodies to produce more of the molecule themselves.

from New Scientist
By netchicken: posted on 14-11-2006

So should we start saving spit? How should it be stored? Does chewing tobacco added to it have a positive or negative affect on this chemical's effectiveness? (Just thinking about all that wasted spit - lol)

Seriously, what an amazing find, because if properly developed it might have amazing benefits with fewer side affects than the current chemical alternatives.

Probably years out from anything significant being developed though I suspect?
By MELtdown: posted on 14-11-2006

Cool. Sometime's if I cut my finger I'll suck on it because I'm cool like that, next time I might have to pay more attention to the pain, and if I should be so lucky as to have two distinct cuts maybe I can experiment :cool::sc
By parrhesia: posted on 16-11-2006

... Quote:
Originally posted by parrhesia
Cool. Sometime's if I cut my finger I'll suck on it because I'm cool like that,

By IAF: posted on 16-11-2006


What's so funny.

By parrhesia: posted on 16-11-2006

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